Monday, December 30, 2019

Profile of Michael Skakel - Part One

Michael Skakel: Michael Skakel should have had it all - wealth, security, friends in high places, but something went terribly wrong. Being a nephew to the Kennedy clan failed to protect him from himself and problems for Michael started early. In an autobiography proposal that he was trying to sell to a publisher, Skakel described his rage, his learning disability, alcoholism and sibling jealousy. Twenty-seven years later, a jury decided that his personal demons led him to bludgeon 15-year-old Martha Moxley to death with a golf club. Silver Spoons: Michael Skakel was born on October 19, 1960 to Rushton and Anne Skakel. He was the middle son of six siblings and grew up in a large home in the gated wealthy community of Belle Haven in Greenwich, Conn. Rushton Skakel Sr., the brother of Ethel Skakel Kennedy, who was married to the late Robert F. Kennedy, was chairman of the Great Lakes Carbon Corp. The Skakels were part of Americas elite, enjoying an exclusive place in society, wealth, and a home in one of the richest towns in the U.S. Anne Skakel: In 1973 Anne Skakel died from cancer. Michael was 12 years old and devastated at the loss of his mother. Anne was a central part of his life and Michael blamed himself for her death, pointing at his poor attention to his prayers as the reason. The balance that Anne had kept inside the Skakel household was gone and a kind of sibling chaos took over. Rushton Skakel spent much of his time at work, leaving the kids on their own or with hired tutors or live-in sitters. Michaels Miserable School Years: Michael was a terrible student, suffering from undiagnosed dyslexia. His father was constantly lecturing him on improving his study skills. He flunked out of numerous private schools and by the age of 13 he was a self described, full-blown daily-drinking alcoholic. Danger Signs: As a kid, Michael had earned the reputation as being violent and quick to lose his temper. He also was known for torturing and killing birds and squirrels then displaying them in an almost ritualistic way. His quick temper and spoiled nature effected his relationship with the neighborhood kids and often parents would disapprove of their children associating with the volatile Skatel boys. Brotherly Rivalry: Tommy, Michaels older brother, was more popular and had a way with the neighborhood girls. According to Mark Furhmans book, Murder in Greenwich there was a strong rivalry between the two brothers, with Tommy often coming out on the top. This was especially difficult for Michael to accept when he found himself attracted to the same girls as his brother. The Murder of Martha Moxley: In October 1975, Tommy and Michael became suspects in the murder of 15-year-old Martha Moxley, a friend and neighbor of the boys. It was mischief night the night before Halloween, and Martha Moxley and friends were out spraying shaving cream and ringing doorbells before stopping over at the Skakels. Martha left the Skakels for home between 9:30 and 11:00 p.m. but never made it. The Golf Club: The following day her bludgeoned body was found under a tree in her yard. Her jeans were pulled down, but no evidence of a sexual assault was found. The weapon, an expensive Toney Penna golf club, was found with a shattered shaft, with a jagged piece of it lodged in Marthas neck. Investigators traced the club to a set belonging the boys deceased mother, Anne Skakel. The Alibi: This discovery put the prime focus on the Skakel household. After interviewing Marthas friends, including the Skakels, the police ruled out Michael Skakel as a suspect because he was at a friends house during the time Martha was murdered. Tommy Skakel and a newly hired tutor, Ken Littleton,who was living at the Skakel home, remained on the top of the suspect list, but no arrests were made in the case. The Drinking Problem: Michaels daily drinking escalated and in 1978 he was arrested in New York for driving while intoxicated. In an agreement with the state to drop the charges, Michael was sent off to Elan School in Poland Spring, Maine where he was treated for alcoholism. Primal Screaming: The Elan School had a series of group therapy and private sessions where students were encouraged to participate in primal screaming and come clean about incidents in their lives which caused them guilt and sorrow. It was during this time at Elan that Michael supposedly admitted to his father and members of the Elan staff that he was involved in Martha Moxleys murder, (a point now denied by his attorney). Sobriety: After Michael left Elan, he continued to battle his alcoholism, entering different rehabilitation centers. In his early 20s he began living a sober life. He was diagnosed with dyslexia and entered Curry College in Massachusetts which focused on students with learning disabilities. After his graduation he married golf pro, Margot Sheridan and spent much of his time preparing and competing in speed skiing events. William Kennedy Smith: In 1991, the Moxley investigation was reopened after rumors circulated during the trial of William Kennedy Smith, that William was at the Skakel home on the night Moxley was murdered. The press was also interested in the case and many of the original principals were interviewed. Although the rumor of Smiths presence in the home proved to false, the public eye was once again focusing in on the Skakel boys, Tommy and Michael.

Sunday, December 22, 2019

Property Of The American Political Thought - 1382 Words

Property in the American Political Thought The concept of property has long been one of the most crucial aspects for the U.S. citizens, as it is a major part of the Constitutional, and, therefore, human rights. Although the perception and understanding of â€Å"property† have been considerably changed, especially in terms of political and philosophical vision, it still has a particular meaning for the Americans. In general, the idea of property is the question of the political thought and conceptualized thinking common for the United States. In most cases, its transformations are connected to the introduction of capitalism and related governmental decision in politics. Therefore, as any other topic, the value of property has undergone harsh debates. In particular, such important figures as James Fenimore Cooper, Ralph Waldo Emerson, and Walt Whitman have developed a fundamental scope of analyses with regard to the property rights in America. In fact, the U.S. civil and property rights have a legal hierarchical organization, where the property rights stay in between the constitutional power and individual civil rights. In the 5th Amendment, the aspect of private property is mentioned as â€Å"nor shall private property be taken for public use without just compensation†(1273). This is the clearest example of private property protection in the United States and its initial value. Besides, the Declaration of Independence relates the property rights to the issues of equality and theShow MoreRelatedJean-Jacques Rousseau and John Locke: Their Relevance for American Society 1811 Words   |  7 Pagesprotect individuals’ rights. Locke, believes that each individual has a right to life, liberty and property. Private property is so vital to Locke because man earns the right to property through labor which shows that not only are individual rights important, but also advancement of individual interests. 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Saturday, December 14, 2019

Congenital Adrenal Hyper Plasia Health And Social Care Essay Free Essays

To, find the clinical presentation of inborn adrenal hyperplasia and to detect the short term response to intervention. Design: Case series survey. Topographic point AND DURATION OF STUDY: The survey extended over a period of one twelvemonth from July 2007 To July 2008 in Paediatric section Chandka Medical College Larkana. We will write a custom essay sample on Congenital Adrenal Hyper Plasia Health And Social Care Essay or any similar topic only for you Order Now MATERIAL AND METHODS: All kids showing with purging desiccation, daze, failure to boom and equivocal genital organs were examined and investigated exhaustively. The chief stay of the diagnosing was raised degree of serum 17OHP in kid with implicative clinical characteristic. Consequence: A sum of 30 kids were found to hold CAH during the survey period. The major clinical characteristics a presentation were purging 8 ( 26.7 % ) , equivocal genital organs 7 ( 23.3 % ) emesis and failure to boom 1 ( 3.3 % ) . All the patients were followed up after induction of intervention and response was observed. Decision: The survey highlights the importance of common clinical symptoms like, purging being the presenting characteristics of CAH and the effectivity of the replacing therapy in bettering life endangering exigencies due to this status. Cardinal WORDS: Congenitaladrenalhyperphase ( CAH ) ,17 hydroxyprogesterone ( 17 OHP ) , cytochrome P 450 protein ( CYP ) . correspondence to: Dr. Shanti Lal, Assistant Professor Pediatricss *Dr. Abdul Ghani Shaikh Assistant Professor Surgery ** Dr. Amanullah Abassi Assistant Professor Urology Chandka Medical College, Larkana dr.shantilal @ yahoo.com Introduction CAH is a familial upset characterized by a lack in the endocrine hydrocortisone and aldosterone and an over production of the endocrine androgen, which is present at birth and affects sexual development. The upset is inherited as an autosomal recessive defect in congenital enzyme synthesis. As such there is history of early neonatal decease in the household. The clinical manifestations of the disease relate to the grade of hydrocortisone lack, aldosterone lack, or lack of both and, in some instances, to the accretion of precursor adrenocortical endocrines. These precursors cause abnormalcies such as masculinization or high blood pressure when nowadays in supraphysiologic concentration many of the enzymes involved in hydrocortisone and aldosterone syntheses are cytochrome p450 proteins designated CYP. CYP21 refers to 21-hydroxylase, CYP11B1 refers to 11-beta-hydroxylase, and CYP17 refers to 17-alpha-hydroxylase. Excess adrenal androgen production begins in early foetal life in authori tative CAH-21 affected babies, and causes unnatural growing of misss ‘ button and masculinisation of the genital-urinary constructions. Badly affected misss may be mistaken for male childs at birth. Affected male childs have no venereal deformities at birth, but continued androgen extra causes remarkably fast organic structure growing. Inappropriately early pubescence leads to premature completion of growing and short concluding grownup height [ 1- 3 ] . Severe signifiers of inborn adrenal hyperplasia are potentially fatal if unrecognised and untreated because of the terrible hydrocortisone and aldosterone lacks that result in salt cachexia, hyponatremia, hyperkalemia, desiccation, and hypotension [ 1,6,7 ] . Females with some signifiers of adrenal hyperplasia ( i.e. , CYP21 lack, CYP11B1, partial 3-beta-hydroxysteroid dehydrogenase lack ) have equivocal genital organs at birth ( authoritative masculinizing adrenal hyperplasia ) or later become virilized in childhood ( simple masculinizing adrenal hyperplasia ) or in adolescence and maturity ( nonclassic masculinizing adrenal hyperplasia ) . Males with CYP21 lack are non by and large identified in the neonatal period because their genital organs are normal. If the defect is terrible, ensuing in salt cachexia, these male babies are seen at 1-4 hebdomads of age because of failure to boom, recurrent emesis, desiccation, and daze. Some babies are ab initio misdiagnosed with stomach flu o r pyloric stricture [ 1,2,6 ] . Hyponatremia and hyperkalemia should raise the possibility of adrenal inadequacy. Two signifiers of adrenal hyperplasia ( i.e. , CYP11B1 lack, CYP17 lack ) consequence in high blood pressure [ 1,2,6,7 ] Congenital adrenal hyperplasia occur among people of all races. Congenital adrenal hyperplasia because all signifiers of inborn adrenal hyperplasia are autosomal recessionary upsets, both sexes are affected with equal frequence [ 1 ] . All kids including neonate who have purging and/or desiccating are diagnosed as acute stomach flu. This consequences in certain congenital mistakes of metamorphosis particularly CAH being overlooked, unsuitably treated and consequences in increasing preventable mortality earlier in life. The intent of survey is to depict our experience of placing CAH in footings of their presentation and short term intervention. Patients AND METHODS This crossectional survey was carried out in paediatric section of Chandka Medical College Larkana from July 2007 to July 2008. The chief purpose of the survey was to happen out the chief manners of presentation of CAH and to see the response of intervention on short term footing. A successful response to replacement therapy observed within a period of two to four was surcease of emesis, need for endovenous fluid therapy and failure to boom. All patients suspected to hold CAH i.e. with clinical characteristics and raised serum degrees of 170HP were included in the survey. A elaborate history ( purging, failure to boom, sibling decease ) followed by thorough physical scrutiny ( blood force per unit area, hydration, misss for equivocal genital organs and male childs for precocious pubescence ) was carried out. Probes done included complete blood count, blood sugar, serum carbamide and electrolytes ( Na 130 – 150 mmol/l ; potassium 3.5 – 4.0 mmol/l ) , karyotyping and serum17OHP degrees ( Normal A ; lt ; 100 ng/dl ) . Classical salt blowing assortment have 17 OHP degrees A ; gt ; 2000 mg/dl ; Classical virilizing A ; gt ; 1000 ng/dl and nonclassical = 100 – 200 ng/dl. Karyotyping was done in patients with equivocal genital organs to set up the diagnosing of CAH in our survey. Classically they had to be female karyotype who was virilized [ 4 ] . Patients that had other grounds for equivocal genital organs and failure to boom like nephritic cannular defects etc were excluded from the survey. All probes were carried out in Pathology Department Chandka Medical College Larkana except 17 OHP and Karyotyping from Agha Khan University Laboratory. All patients were treated with replacing therapy including cortisol 50 mg/M2 stat followed by 1000 milligram / M2/ twenty-four hours 6 hourly, tapered to 20 milligrams / M2 /day. In salt losing assortment ab initio normal saline 20 milliliter / kilogram was repeated if necessary followed by florinated steroid ( fludrocortisone – 0.15 milligram / M2 ) was given. The response to the criterion paediatric pattern was studied. Consequence Sum of 30 patients were diagnosed to hold CAH. The age scope of kids was from 4 to 180 yearss with a average age at the clip of presentation was 39.67 yearss. ( table-1 -fig-1 ) the sex distribution was about equal ( table-2-fig-2 ) . The chief clinical characteristics included emesis, equivocal genital organ, desiccation and failure to boom ( table-3 ) . Probes of all the patients showed raised degrees of 17OHP. Karyotyping was done in patients with equivocal genital organs. All instances diagnosed to hold CAH were put on replacing therapy. Short term response was observed after a period of 4 hebdomads. All instances showed positive response shortly after the induction of therapy. The patients who presented with failure to boom started deriving weight. As emesis was the major symptom at presentation, it responded good to intervention. Children showing with equivocal genital organs were put on replacing therapy and subsequently referred for surgical intervention i.e. clitoroplasty. Discussion CAH is chiefly disease of early babyhood as the average age of presentation in our survey is 39 yearss. It is widely present all over the universe with equal male to female ratio [ 1,2 ] . The present survey besides shows the same consequence with average age of presentation being 39.67 yearss. However there is little male preponderance in our survey ( 56.7 % ) . Clinical characteristics observed in this survey are in conformance with other surveies.The frequent manners of presentation include purging, equivocal genital organ ( Fig-1 ) , daze and failure to boom [ 1,2 ] . Some patients presented merely one symptom and other with two or three marks and symptoms together Table-1: Outstanding characteristics of the 30 instances studied. Average age of presentation ( yearss ) 39.67 Male: female ratio 1.5:1 Major symptom/sign ( purging n equivocal genital organs 10 ( 33.3 % ) Positive Family history/Neonatal decease 10 ( 33 % ) Figure: 1 Equivocal Genitalia Ambiguous Genitalia Table-2: Gender distribution. No of Patients Percentages Female 13 43.3 % Male 17 56.7 % Table-3: Presenting characteristics of the instances. No of Patients Percentages Vomiting 8 26.7 % Equivocal genital organs 7 2.3 % Vomiting and equivocal genital organs 10 33.3 % Failure to boom 1 3.3 % Daze 4 13.3 % Figure: 2 Equivocal Genitalia Ambiguous Genitalia Table-4: Treatment. No of Patients Percentages Hydrocortisone 7 23.3 % Hydrocortisone and fluodrocortisone 23 76.7 % Most of the kids in our survey presented with relentless purging since birth. This was ab initio thought of, because of enteric obstructor like pyloric stricture or simple regurgitation of milk, which is much more common in immature babies. Vomiting, as the lone presenting characteristic makes the diagnosing small hard but it is frequently associated with equivocal genital organs particularly in females i.e. clitoromegaly. Females are recognized because of equivocal genital organs, but males have normal genital organs and are non diagnosed until subsequently, frequently with a salt losing crisis [ 8 ] . Another of import clinical mark was failure to boom. It was present along with emesis and besides as the lone presenting characteristic. Salt also-rans besides presented in a province of daze. The criterion for diagnosing was raised degrees of 17OHP [ 4,5 ] . As the diagnostic installations are easy available, diagnosing at an early age with induction of intervention is possible. 21 h ydroxylase lacks ( CYP 21 ) is the most common signifier. Approximately 50 % of patients with authoritative inborn adrenal hyperplasia from CYP 21 lack have salt blowing due to inadequate aldosterone synthesis. One tierce of patients in our survey presented with grounds of salt blowing [ 8 ] . Bing an autosomal recessionary upset, there is 25 % opportunity that the status will be found in the siblings of the patient. In our survey there was an increased incidence ( 33 % of the patients ) of upset in siblings of patients in our survey. Incidence in all the patients could non be found as some of the patients were the first issues of the parents. Even in those, in whom the upset was suspected, merely clinical diagnosing was thought of on the footing of early neonatal decease. However attempts should be made in set uping antenatal diagnosing possible as intrauterine Decadron during the first trimester helps in cut downing opportunities of equivocal genital organ. This is done via chorio nic villus trying in first trimester at 8 hebdomads gestation [ 1-3 ] . Amniocentesis at 12 hebdomads can besides be done. As a antenatal direction step, Dexamethasone ( 10 – 20 ug /kg / twenty-four hours ) at diagnosing of gestation is started. Stop the intervention in male childs and unaffected misss. Affected misss in whom Decadron should be continued, maternal urinary estriol ( mark A ; lt ; 375 ng/ deciliter ) are followed up [ 8,9 ] . Decision Following points are drawn from our survey:  · CAH is fundamentally a disease of early babyhood  · The usual presenting ailments are really common like purging, desiccation and failure to boom.  · Prompt intervention with replacing therapy can efficaciously abort a life endangering province. How to cite Congenital Adrenal Hyper Plasia Health And Social Care Essay, Essay examples

Friday, December 6, 2019

Parts of Speech Persuasive Essay Example For Students

Parts of Speech Persuasive Essay Traditional grammar classifies words based on eight parts of speech: the verb, the noun, the pronoun, the adjective, the adverb, the preposition, the conjunction, and the interjection. Each part Of speech explains not What the word is, but how the word is used. In fact, the same overdo can be a noun in one sentence and a verb or adjective in the next The next few examples show how a words part Of speech can change from one sentence to the next, and following them is a series of sections on the individual parts Of speech, followed by an exercise. Books are made Of ink, paper, and glue. In this sentence, books is a noun, the subject of the sentence. Deborah waits patiently while Bridget books the tickets. Here books is a verb, and its subject is Bridget. We walk down the street. In this sentence, walk is a verb, and its subject is the pronoun we. The mail carrier stood on the walk. In this example, uvula is a noun, which is part of a prepositional phrase describing where the mail carrier stood. The town decided to build a new jail. Here jail is a noun, which is the object of the infinitive phrase to build. The sheriff told us that if we did not leave town immediately he would jail us. Here jail is part Of the compound verb would jail. They heard high pitched cries in the middle of the night. In this sentence, cries is a noun acting as the direct object of the verb heard. The baby cries all night long and all day long. But here cries is a verb that describes the actions of the subject of the sentence, the baby, An adjective adjective modifies a noun or a pronoun by describing, identifying, or quantifying words. An adjective usually precedes the noun or the pronoun which it modifies. In the following examples, the highlighted words are adjectives:The truck-shaped alone floated over the treetops. Mrs Morrison papered her kitchen walls vivid hideous wall paper. The small boat foundered on the wine dark sea. The coal mines are dark and dank. Many stores have already begun to play irritating Christmas music. A battered music box sat on the mahogany sideboard. The back room was filled with large, yellow rain boots. An adjective can be modified by an adverb, or by a phrase or clause functioning as an adverb. In the sentence husband knits intricately patterned mittens. For example, the adverb intricately modifies the adjective pattered. Some nouns, many pronouns, and many participle phrases can also act as adjectives. In the concentrations listened to the muffled sounds of the radio hidden under her pillow. For example, both highlighted adjectives are past participles. Grammarians also consider articles (the, a, an) to be adjectives. Possessive Adjectives possessive adjective (my, your, his, her, its, our, their) is similar or identical to a possessive pronoun: however, it is used as an adjective and modifies a noun or a noun phrase, as in the following sentences:l ant complete my assignment because dont have the textbook. In this sentence, the possessive adjective my modifies assignment and the noun phrase my assignment functions as an object. Note that the possessive pronoun form mine is not used to modify a noun or noun phrase. What is your phone number. Here the possessive adjective your is used to modify the noun phrase phone number; the entire noun phrase your phone number is a subject complement. Note that the possessive pronoun form yours is not used to modify a noun or a noun phrase. The bakery sold his favorite type of bread. Revolutionary war involement EssayThe diagram below shows some of the more important speech organs. This kind of diagram helps us to understand what we observe in others but is less useful in understanding our own speech Scientists can now place small cameras into the mouths of experimental subjects, and observe some of the physical movements that accompany speech. But most Of LIST moue our vocal organs by reflexes or a sense of the sound we want to produce, and are not likely to benefit from watching movement in topical fold. The diagram is a simplified cross-section through the human head which we could not see in reality in a living speaker, though a simulation might be instructive. But eve do observe some external signs Of speech sounds apart from what we hear. MORPHOLOGY Morphology is a field of linguistics focused on the study of the forms and formation of words in a language. A morpheme is the smallest indivisible unit of a language that retains meaning. The rules of morphology within a language tend to be relatively regular, so that if one sees then morphemes for the first time, for example, one can deduce that it is likely related to the word morpheme. There are three main types of languages when it comes to morphology: two theses reapportionments, meaning that words are dad up of connected morphemes, One type of polytheistic language is a fusion or inflected language, in which morphemes are squeezed together and often changed dramatically in the process. English is a good example off fusion language. The other type of polytheistic language is an agglutinative language, in which morphemes are connected but remain more or less unchanged many Native American languages, as well as Swahili, Japanese, German and Hungarian, demonstrate this. At the other end of the spectrum are the analytic or isolating languages, in which a great majority of morphemes main independent words Mandarin is the best example of this. Morphology studies all of these different types of languages and how they relate to one another as well. This can be a confusing concept, so an example may be helpful. Looking at the morphology of English, which is not a particularly inflected language in its modern form, but retains a number Of remnants, we could create the word frighteningly, which is made up of four morphemes: fright, Which sis noun; en, Which converts the noun to a verb; ins, Which converts it to an adjective; and lay, which converts it to an adverb. Over time, languages end to become less and less inflected particularly when a lot Of intercultural contact occurs. In morphology, this is because the languages become criticized as various pidgins used for communicating between disparate groups become natively spoken, and inter-communication in the pidgins is facilitated by dropping inflections. Although you may be used to seeing certain forms in a specific context such as conjugations at the end of a word they can express themselves in a number of different ways. Aside from the English use of prefix and suffix, words can also be inflected by changing the sound of a vowel called n umlaut or by placing an affix right in the middle of the word. Affixes can also be quite lengthy, not just little bites of sound in Quiches, for example, there are a number oft-syllable affixes. Though most people never formally study morphology, it is something native speakers understand intuitively. Any time a person learns a narrowed and immediately comes up with any number of forms for that word ? past tense, plural, a noun form they are applying the rules of morphology subconsciously to determine what the new form should be. SYNTAX: Syntax, the arrangement Of words in sentences, clauses, and phrases, and the duty of the formation of sentences and the relationship of their component parts. In a language such as English, the main device for showing the relationship among words is word order; e. G. , in The girl loves the boy, the subject is in initial position, and the Object follows the verb. Transposing them changes the meaning. In many other languages. Case markers indicate the grammatical relationships. In Latin, for example, The girl loves the boy may be paella perfume mat with the girl in initial position, or perfume paella mat with the boy in initial position, or mat paella perfume, mat perfume paella, or paella mat perfume.